Scientific research has shown that cannabidiol does not operate, or at least operates very weakly, on the CB1 and CB2 cannabinoid receptors in the brain. Those two receptors are the ones most powerfully influenced by THC, which creates the cognitive changes associated with feeling “high” or “stoned.” In fact, the CBD found in dog treats counteracts and suppresses the effects of THC. Cannabidiol binds to different receptors that suppress pain, moderate body temperature, alleviate pain, and lessen anxiety, among other effects.
Our products are 100% free of pesticides, fungicides, and herbicides. We’re are extremely careful and only source from 100% organic farms. And just to make sure pesticides have never come in contact, we routinely have our hemp tested by a third party for potency and the presence of any toxins/pesticides. You can see the results on the certificate of analysis found on our website.

With that said, cannabis remains a Schedule I drug in the US, and that is why veterinarians are hesitant to prescribe any cannabis-based medicine. It will take at least half a decade to see any promising scientific advancement regarding medicinal cannabinoid use for pets. Until then, people will continue to rely on the testimonials of dog owners who have tried these products.


Our Edibites are infused with our full spectrum certified USDA organic CBD hemp oil which is extracted from our proprietary strain of hemp, PR-33. PR-33 is grown at our joint-venture certified USDA organic hemp farm in eastern Colorado and was selected because it’s cannabinoid profile was the most optimal for pets. In order for CBD products to be as beneficial as possible, every cannabinoid naturally found in the hemp plant must be present, THC included. This is because all of the cannabinoids in the hemp plant work together in what is called the “entourage effect,” this is why Pet Releaf never uses CBD isolate, CBD alone loses the majority if it’s medicinal benefits. The PR-33 strain is extremely high in the beneficial cannabinoid CBD and extremely low in THC at an almost undetectable level of 0.1%. PR-33 is a proprietary strain and will only ever be found in Pet Releaf products. We extract our CBD hemp oil using a super critical CO2 method, meaning we only use pressurized air to remove the CBD from the plant and never any toxic solvents or chemicals. Our CBD hemp oil uses the flowers, leaves, and some seeds so that our products contain the full spectrum CBD that is extracted from the plant as well as the protein benefits of the seeds.
Veterinarians’ views on pets being treated with CBD vary widely, with some citing the lack of scholarly literature on it specifically in relation to pets. Meanwhile, the Food and Drug Administration (FDA), which regulates pet food in the US, decidedly does not approve of CBD. “With regard to its use in food, FDA's position is that CBD … is an unapproved drug, hence any food (including animal feed or pet food) containing it would be actionable as an adulterated product,” wrote David A. Dzanis, DVM, PhD, DACVN, in a recent Petfood Insights column.
Cannabidiol (CBD) interacts with receptors in the brain, central nervous system, and organs and acts as an anti-inflammatory and immune-boosting agent. There are a number of reasons why your pup would need an anti-inflammatory agent. Whether it’s to aid in post-operative care or alleviate pain associated with illness or disease, CBD has been proven to fight inflammation in dogs (and people).
Yes, they do! The reason you won’t find CBD on the label is that CBD is not the best term to describe these products anymore. There are hundreds of different molecules in hemp that all contribute to the overall therapeutic effects. So many companies are now calling these products Full Spectrum Hemp, Hemp extract, or Phytocannabinoid-rich (PCR) Oil instead of CBD hemp.
And then, finally, there is also a significant body of research that suggests CBD can be helpful in fighting cancer and getting rid of tumors. Of course, nothing has come forward to state for sure that CBD will cure cancer, but we do know that it is helpful in treating the nausea, loss of appetite, and pain that can result from the cruel disease and the often harsh treatments we now have for it.
Forskolin; earlier I have stated that it is the side product of the cannabidiol oil and if you have been ever used the CBD oil and hemp oil then probably you could be able to understand the quality of the verifiedforskolin.com. Before taking you further, you must have been thinking that if any product like Forskolin has the immense quality to create some outstanding benefits for the human body, then it would be grateful. This exceeding product has been discovered to ensure the benefits which have been impeccable since it has been started to be used for the various purpose. Check these points for the same;

Joey, I don’t know if your gf and Phoebe has went on their trip, but everything that I’ve read it takes about 2 weeks for CBD to build up in a dogs system and since your dog is a shitzu I would suggest a 1.5mg bag of treats from where ever you get them from. She is a smaller dog and there are 2 dosages I’ve seen. 1.5mg for dogs up to 45 or so and 5mg for dogs 45 +. As for the liquid I have no idea as I haven’t researched that. It sucks that no one replied to your question. I hope you were able to find the answer if they flew already. Good luck!
CBD Oil for Dogs & Cats – Benifits and Uses – Researchers have shown that CBD can act as an anti inflammatory, anticonvulsant, antiemetic, antioxidant, anxiolytic and antipsychotic agent. Therefor it has been used to treat many ailments including: pain & inflammation, epilepsy, vomiting, nausea, stress & anxiety, arthritis, skin conditions & allergies, aging & wellness issues. Find out more on the health benefits of CBD here.
What is HolistaPet CBD Oil? – Cannabidiol (CBD) is one of the most highly researched compounds found in the industrial hemp plant (Cannabis Sativa). This natural occurring cannabinoid is gaining more popularity over the past few years because of it’s amazing health benefits. Our CBD Oil For Dogs and our delicious CBD dog treats contain NO THC, are non-psychoactive and will NOT get your pet “High”.
cbdMD dog treats are a better deal when compared to what I spent on veterinarian appointments and prescription medication before I knew that Rodrigo was a candidate for natural solutions.  The first time I gave him prescription medication, he spaced out, slipped out the door at night, and got lost in the woods while fireworks were going off around us.  I found him, but these were the scariest moments I've had with him.  With these CBD dog treats, he was sleeping peacefully 30 minutes after having a snack despite the fireworks.
The calming effects of CBD work very well with high-strung dogs who struggle with separation anxiety, depression, and noise phobias. Dogs who experience severe separation anxiety are often depressed or anxious when their guardians leave them alone and it may result in disruptive and destructive behaviors, such as drooling, urinating, barking, chewing on objects and pacing. 
Dogs with chronic inflammation and joint troubles can also benefit tremendously from having some CBD added into their diets. CBD is a known pain reliever, and a natural one at that, so it can go a long way in relieving the aches and pains your dog might feel on a daily basis, and it has also been found to help treat inflammation and give pups a more comfortable life.
First, we need to outline the distinction between CBD and THC. Cannabidiol is not the same thing as tetrahydrocannabinol. Tetrahydrocannabinol, or THC, is the major reason why words like “cannabis,” “marijuana,” “pot,” and “weed” provoke immediate and negative reactions among the general populace. Like CBD, THC is a cannabinoid. THC is a psychoactive compound that produces the sensations of being “stoned.”
The company used to call them biscuits, but didn’t want them to be confused with regular ol’ dog treats because they contain 2mg of phytocannabinoid-rich hemp oil (sourced directly from a Colorado Department of Agriculture provider) each. “These are not training treats. These are health products or supplements,” Polly Patterson, COO/CMO of HHPC, tells Leafly, adding that they were created in partnership with veterinarians. The green-lipped mussel ingredient is a unique and special touch—it is a rich source of glucosamine and chondroitin, which are popular supplements for aging dogs with aching joints and muscle pain.
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