Comprehensive research shows that CBD products have a low side-effect profile. However, the one notable concern is CBD's interaction with enzymes in the liver that metabolize the majority of pharmaceuticals. In most cases, studies have shown that this interaction is uncommon, but it can occur. By delaying the rate a pharmaceutical is metabolized, you potentially raise its potency and its side effects. This could be one of the reasons, CBD is able to lower the use of other pharmaceuticals.
The calming effects of CBD work very well with high-strung dogs who struggle with separation anxiety, depression, and noise phobias. Dogs who experience severe separation anxiety are often depressed or anxious when their guardians leave them alone and it may result in disruptive and destructive behaviors, such as drooling, urinating, barking, chewing on objects and pacing. 
First, we need to outline the distinction between CBD and THC. Cannabidiol is not the same thing as tetrahydrocannabinol. Tetrahydrocannabinol, or THC, is the major reason why words like “cannabis,” “marijuana,” “pot,” and “weed” provoke immediate and negative reactions among the general populace. Like CBD, THC is a cannabinoid. THC is a psychoactive compound that produces the sensations of being “stoned.”

Let’s start with the basics. Phytocannabinoids are the naturally occurring cannabinoids found in the cannabis and hemp plants. What’s a cannabinoid, you ask? Well, to put it simply they are the chemical compounds produced by cannabis flowers that scientists and doctors have discovered can be useful for treating a variety of ailments, from nausea to arthritis. Now, there are two cannabinoid, Cannabidiol (CBD) and tetrahydrocannabinol (THC), but the one that seems to have the most health benefits is the CBD. Still with us so far? Ok good!
Comprehensive research shows that CBD products have a low side-effect profile. However, the one notable concern is CBD's interaction with enzymes in the liver that metabolize the majority of pharmaceuticals. In most cases, studies have shown that this interaction is uncommon, but it can occur. By delaying the rate a pharmaceutical is metabolized, you potentially raise its potency and its side effects. This could be one of the reasons, CBD is able to lower the use of other pharmaceuticals.
“The pet product market is very excited about CBD products,” said Brad Solomon, founder/partner of Prana Pets, quoted in the Pet Product News article. “Many retailers want to carry these products, but they are concerned about the legality of CBD. Everybody we speak to agrees about all the amazing benefits associated with this category. Our client testimonials are enough for us. Every client who has tried our CBD products is experiencing positive results.”
Our Edibites are handmade and baked in small batches in the Pet Releaf Colorado kitchen. After a year of extensive research and development, we’ve created a proprietary cooking method to ensure that the way our Edibites are baked does not impact the beneficial cannabinoids found in our certified USDA organic full spectrum CBD hemp oil. Whether your dog is in incredible health or is suffering from illness or injury, our Edibites are the immune system turbo boost they need.  They contain no fillers, no chemical preservatives and no 12 syllable ingredients. Pet Releaf Edibites are also corn, soy, dairy, and wheat free as well as being completely vegan. Our Edibites aren’t just made in the USA they are also farmed in the USA with 95% of our ingredients coming from American farmers.
Treatibles’ exceptional full spectrum oil is sourced from our own organic hemp fields across four states. Along with master cultivator partners, we have created a proprietary formula that contains a beneficial blend of naturally occurring compounds, producing truly distinct oil. All Treatibles products are virtually free of THC, non-psychoactive, and non-toxic.
Our Edibites are infused with our full spectrum certified USDA organic CBD hemp oil which is extracted from our proprietary strain of hemp, PR-33. PR-33 is grown at our joint-venture certified USDA organic hemp farm in eastern Colorado and was selected because it’s cannabinoid profile was the most optimal for pets. In order for CBD products to be as beneficial as possible, every cannabinoid naturally found in the hemp plant must be present, THC included. This is because all of the cannabinoids in the hemp plant work together in what is called the “entourage effect,” this is why Pet Releaf never uses CBD isolate, CBD alone loses the majority if it’s medicinal benefits. The PR-33 strain is extremely high in the beneficial cannabinoid CBD and extremely low in THC at an almost undetectable level of 0.1%. PR-33 is a proprietary strain and will only ever be found in Pet Releaf products. We extract our CBD hemp oil using a super critical CO2 method, meaning we only use pressurized air to remove the CBD from the plant and never any toxic solvents or chemicals. Our CBD hemp oil uses the flowers, leaves, and some seeds so that our products contain the full spectrum CBD that is extracted from the plant as well as the protein benefits of the seeds.
While hemp seed oil is made from the seeds of the plant, it has very little CBD, not enough to provide pain or anxiety relief.  I've been using CBD oil with my dogs for a few years with my dogs and I love the idea of incorporating CBD dog treats into their diet because treats can taken on a drive, a walk, or to the vet's office with no mess.  I've spilled a 1/4 of a bottle of essential oils into my bag once.  That sucked.  It would suck even more if it was a bottle of CBD oil.  CBD dog treats are also an excellent option for dogs, like Sydney, that don't like CBD oil.

And then, of course, there are the more urgent medical conditions that might make CBD a necessity. Studies have shown that CBD is an especially effective way to treat epilepsy, and when given to epileptic dogs it can help to improve their quality of life dramatically. The research available suggests that not only can a steady CBD treatment reduce the number of seizures and epileptic dog experiences, but it can, in time, even get rid of them all together. More evidence is needed before a definitive statement can be made regarding that, but everything we know now certainly looks promising.
cbdMD dog treats are a better deal when compared to what I spent on veterinarian appointments and prescription medication before I knew that Rodrigo was a candidate for natural solutions.  The first time I gave him prescription medication, he spaced out, slipped out the door at night, and got lost in the woods while fireworks were going off around us.  I found him, but these were the scariest moments I've had with him.  With these CBD dog treats, he was sleeping peacefully 30 minutes after having a snack despite the fireworks.
CBD Pet Spray Pain Relief PAIN RELIEF ORAL SPRAY WITH CBD 99% Pure CBD Oil with 60mg Infused Zero THC 8ml Oral Spray Natural Peppermint Flavor Oral absorption is up to 90% effective, allowing your body to utilize all the necessary nutrients. Through oral absorption, nutrients go directly into the blood stream and then into the cells within a matter of minutes. An oral spray made with natural ingredients combined with CBD to temporary relieve minor aches & pains. Scientifically Tested to be Safe & Effective! Container: 8ml Spray bottle How to Use: Shake bottle. Pets spray 2 sprays into mouth For best results spray under tongue, hold for a few seconds, then swallow. Use twice daily as a dietary supplement. To clean spray rinse under warm water. Do not use if seal is broken. Store in cool dry place. KEY BENEFITS CBD PAIN RELIEF: Reducing vomiting & nausea, Suppresses muscle spasms, Reduce seizures and convulsions MANY USES: Relieves canker sores, cheek bites, & pain from dentures or braces. CONVIENIET PACKAGING: On the go pain relief! Easy to carry and travel with.
Our CBD Dog treats are infused with high quality, full spectrum CBD oil extracted from industrial hemp in Colorado. Be confident that we use natural organic ingredients in our CBD Dog treats. Key super food ingredients such as Turmeric Powder, Boswellia, Hemp Seed Powder, and Flax seed combined with pure CBD oil makes a powerful combination. You can trust in HolistaPet to deliver the highest quality CBD for dogs.

Kimberly Gauthier is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. Kimberly is also a member of the following affiliate advertising programs: Bonnie and Clyde Pet Goods, Ewegurt, FullBucket Daily Canine Powder, Herbsmith, Inc, IrieCBD, Natural Pet Organics, NomNomNow, PawStruck.com, Pet’s Best Pet Insurance, Plant Therapy, Raw Paws Pet Food, Scout and Zoe’s, Simply Earth. I also have a relationship with Darwin’s Natural Pet Products as a customer; please note that Darwin’s Pet does not give me free dog food.

My female pitbull momma and her puppies have suffered a severe trauma involving the suicide of my “husband”, their pack leader. They were present when he shot himself and were there truing to get him up and stayed by his side for afloat 2 hours before i got home… licking ands nudging at him… laying by his side crying when i got home. We were displaced for biohazard cleanup and obvious reasons but the dogs remained in the home… they lay in his spot where he wad discovered as are very distant from each other at times, aggressive more than normal, visually depressed, crying and whining… I was told to try puppy pot pulls but unsure of the type to purchase. I love in Arizona and honestly, not to worried if its legal. Due to the unexpectedly/untimely death and financial obligations, i can’t afford any type of training/grieving therapy. What would you recommend? There are 3 puppies and one momma. Puppies are 5.5 months (9/30/17) and about 42-46 pounds and mom is 3 years old (9/22/14) and about 49 pounds. All haves shots, very checked regularly… 100% full bred pit bulls. Any advice is welcomed as long ad is positive and helpful. No negative contents please as this is a very sensitive subject already and my fur-babies are vey important to me. https://uploads.disquscdn.com/images/4966652a3d01673fcd0799182c36665e895478eeddbb4065b59bc0f4f813fcbe.jpg

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