The size and body weight of a person have little to do with your tolerance to cannabis oil. Be aware that when treating with cannabis oil it is also likely it will lower your blood pressure. If you are currently taking a blood pressure medication it's possible you will no longer need to take it once you start the cannabis oil. Closely monitor your blood pressure to make sure you can stop taking your current medication.
Nineteen responses met the inclusion criteria for the study: a diagnosis of epilepsy and current use of CBD-enriched cannabis. The average number of anti-epileptic drugs tried before using CBD cannabis was 12. Sixteen (84 percent) of the 19 parents reported a reduction in their child’s seizure frequency while taking CBD cannabis. Of these, two (11 percent) reported complete seizure freedom, eight (42 percent) reported a greater than 80 percent reduction in seizure frequency, and six (32 percent) reported a 25–60 percent seizure reduction.
For this study, 24 people with social anxiety disorder received either 600 milligrams (mg) of CBD or a placebo an hour and a half before performing a simulated public speaking test. Additionally, 12 other people with social anxiety disorder performed the same test without receiving any CBD treatment. Results revealed that pre-treatment with CBD significantly reduced anxiety, cognitive impairment, and discomfort while participants were delivering their speech.

If you’ve experimented with other forms of cannabis before, your sensitivity to THC is a key factor in what kind of oil to choose. If you enjoy the typical “high”, picking a THC-rich oil would kick that up a notch, whereas oils with higher concentrations of CBD often have reduced THC values and therefore feel more toned down. It’s recommended that most people start with a CBD-rich oil or an evenly balanced CBD-THC oil, observe, and then gradually increase the amount of THC. 
Some individuals have been found to have mutations on the CNR1 gene, which is responsible for coding the CB1 receptor (a type of receptor in cells throughout your body that interacts with cannabinoids). Issues with the CNR1 gene can ultimately result in a poorly functioning endocannabinoid system, which is an important variable when figuring out how to use CBD oil.
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